1CX3
SOLUTION STRUCTURE OF A COMPLEX BETWEEN D(ATGCAT)2 AND THE ANTITUMOR BISNAPHTHALIMIDE LU-79553
Summary for 1CX3
Entry DOI | 10.2210/pdb1cx3/pdb |
Descriptor | DNA (5'-D(*AP*TP*GP*CP*AP*T)-3'), N,N'-(3,7-DIAZANONYLENE)-BIS-NAPHTHALIMIDE (2 entities in total) |
Functional Keywords | topoisomerase, anticancer, dna, naphthalimide, intercalation, deoxyribonucleic acid |
Total number of polymer chains | 2 |
Total formula weight | 4139.05 |
Authors | Gallego, J.,Reid, B.R. (deposition date: 1999-08-27, release date: 1999-11-19, Last modification date: 2024-05-22) |
Primary citation | Gallego, J.,Reid, B.R. Solution structure and dynamics of a complex between DNA and the antitumor bisnaphthalimide LU-79553: intercalated ring flipping on the millisecond time scale. Biochemistry, 38:15104-15115, 1999 Cited by PubMed: 10563793DOI: 10.1021/bi9915869 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
Download full validation report