1CLU

H-RAS COMPLEXED WITH DIAMINOBENZOPHENONE-BETA,GAMMA-IMIDO-GTP

Summary for 1CLU

Entry DOI	10.2210/pdb1clu/pdb
Descriptor	TRANSFORMING PROTEIN P21/H-RAS-1, MAGNESIUM ION, 3-AMINOBENZOPHENONE-4-YL-AMINOHYDROXYPHOSPHINYLAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (4 entities in total)
Functional Keywords	gtp hydrolase, signal transduction, cancer, g-domain, hydrolase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	19655.99
Authors	Ahmadian, M.R.,Zor, T.,Vogt, D.,Kabsch, W.,Selinger, Z.,Wittinghofer, A.,Scheffzek, K. (deposition date: 1999-05-03, release date: 1999-05-28, Last modification date: 2023-08-09)
Primary citation	Ahmadian, M.R.,Zor, T.,Vogt, D.,Kabsch, W.,Selinger, Z.,Wittinghofer, A.,Scheffzek, K. Guanosine triphosphatase stimulation of oncogenic Ras mutants. Proc.Natl.Acad.Sci.USA, 96:7065-7070, 1999 Cited by PubMed: 10359839 DOI: 10.1073/pnas.96.12.7065 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation