1B6C

CRYSTAL STRUCTURE OF THE CYTOPLASMIC DOMAIN OF THE TYPE I TGF-BETA RECEPTOR IN COMPLEX WITH FKBP12

Summary for 1B6C

Entry DOI	10.2210/pdb1b6c/pdb
Descriptor	FK506-BINDING PROTEIN, TGF-B SUPERFAMILY RECEPTOR TYPE I, SULFATE ION, ... (4 entities in total)
Functional Keywords	complex (isomerase-protein kinase), receptor serine/threonine kinase, complex (isomerase-protein kinase) complex, complex (isomerase/protein kinase)
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm: P62942 Membrane; Single-pass type I membrane protein: P36897
Total number of polymer chains	8
Total formula weight	203412.85
Authors	Huse, M.,Chen, Y.-G.,Massague, J.,Kuriyan, J. (deposition date: 1999-01-13, release date: 1999-06-15, Last modification date: 2024-02-07)
Primary citation	Huse, M.,Chen, Y.G.,Massague, J.,Kuriyan, J. Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12. Cell(Cambridge,Mass.), 96:425-436, 1999 Cited by PubMed: 10025408 DOI: 10.1016/S0092-8674(00)80555-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation