1B3O
TERNARY COMPLEX OF HUMAN TYPE-II INOSINE MONOPHOSPHATE DEHYDROGENASE WITH 6-CL-IMP AND SELENAZOLE ADENINE DINUCLEOTIDE
Summary for 1B3O
Entry DOI | 10.2210/pdb1b3o/pdb |
Descriptor | PROTEIN (INOSINE MONOPHOSPHATE DEHYDROGENASE 2), 6-CHLOROPURINE RIBOSIDE, 5'-MONOPHOSPHATE, SELENAZOLE-4-CARBOXYAMIDE-ADENINE DINUCLEOTIDE, ... (5 entities in total) |
Functional Keywords | dehydrogenase, impd, impdh, guanine nucleotide synthesis |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 113917.74 |
Authors | Colby, T.D.,Vanderveen, K.,Strickler, M.D.,Goldstein, B.M. (deposition date: 1998-12-14, release date: 1999-04-12, Last modification date: 2024-04-03) |
Primary citation | Colby, T.D.,Vanderveen, K.,Strickler, M.D.,Markham, G.D.,Goldstein, B.M. Crystal structure of human type II inosine monophosphate dehydrogenase: implications for ligand binding and drug design. Proc.Natl.Acad.Sci.USA, 96:3531-3536, 1999 Cited by PubMed: 10097070DOI: 10.1073/pnas.96.7.3531 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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