1ADS
AN UNLIKELY SUGAR SUBSTRATE SITE IN THE 1.65 ANGSTROMS STRUCTURE OF THE HUMAN ALDOSE REDUCTASE HOLOENZYME IMPLICATED IN DIABETIC COMPLICATIONS
Summary for 1ADS
Entry DOI | 10.2210/pdb1ads/pdb |
Descriptor | ALDOSE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total) |
Functional Keywords | oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P15121 |
Total number of polymer chains | 1 |
Total formula weight | 36510.55 |
Authors | Wilson, D.K.,Quiocho, F.A. (deposition date: 1992-07-08, release date: 1993-10-31, Last modification date: 2024-02-07) |
Primary citation | Wilson, D.K.,Bohren, K.M.,Gabbay, K.H.,Quiocho, F.A. An unlikely sugar substrate site in the 1.65 A structure of the human aldose reductase holoenzyme implicated in diabetic complications. Science, 257:81-84, 1992 Cited by PubMed: 1621098PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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