1A8G
HIV-1 PROTEASE IN COMPLEX WITH SDZ283-910
Summary for 1A8G
Entry DOI | 10.2210/pdb1a8g/pdb |
Related PRD ID | PRD_000417 |
Descriptor | HIV-1 PROTEASE, benzyl [(1R)-1-({(1S,2S,3S)-1-benzyl-2-hydroxy-4-({(1S)-1-[(2-hydroxy-4-methoxybenzyl)carbamoyl]-2-methylpropyl}amino)-3-[(4-methoxybenzyl)amino]-4-oxobutyl}carbamoyl)-2,2-dimethylpropyl]carbamate (3 entities in total) |
Functional Keywords | acid proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Human immunodeficiency virus 1 |
Total number of polymer chains | 2 |
Total formula weight | 22487.55 |
Authors | Kallen, J.,Billich, A.,Scholz, D.,Auer, M.,Kungl, A. (deposition date: 1998-03-24, release date: 1998-07-15, Last modification date: 2024-05-22) |
Primary citation | Ringhofer, S.,Kallen, J.,Dutzler, R.,Billich, A.,Visser, A.J.,Scholz, D.,Steinhauser, O.,Schreiber, H.,Auer, M.,Kungl, A.J. X-ray structure and conformational dynamics of the HIV-1 protease in complex with the inhibitor SDZ283-910: agreement of time-resolved spectroscopy and molecular dynamics simulations. J.Mol.Biol., 286:1147-1159, 1999 Cited by PubMed: 10047488DOI: 10.1006/jmbi.1998.2533 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report