173D

MULTIPLE BINDING MODES OF ANTICANCER DRUG ACTINOMYCIN D: X-RAY, MOLECULAR MODELING, AND SPECTROSCOPIC STUDIES OF D(GAAGCTTC)2-ACTINOMYCIN D COMPLEXES AND ITS HOST DNA

173D の概要

• エントリーDOI: 10.2210/pdb173d/pdb
• 関連するPDBエントリー: 172D 1A7Y 1A7Z 1DSC 1DSD 1FJA 1I3W 1L1V 1MNV 1OVF 1QFI 1UNJ 1UNM 209D 2D55 316D
• 関連するBIRD辞書のPRD_ID: PRD_000001
• 分子名称: DNA (5'-D(*GP*AP*AP*GP*CP*TP*TP*C)-3'), ACTINOMYCIN D (3 entities in total)
• 機能のキーワード: actinomycin, antibiotic, antitumor, anticancer, chromophore, depsipeptide, dna-antibiotic complex, dna/antibiotic
• 由来する生物種: STREPTOMYCES ANTIBIOTICUS
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 7436.13

構造登録者

Kamitori, S.,Takusagawa, F. (登録日: 1994-04-18, 公開日: 1994-10-15, 最終更新日: 2024-07-10)

• 主引用文献: Kamitori, S.,Takusagawa, F.; Multiple Binding Modes of Anticancer Drug Actinomycin D: X-Ray, Molecular Modeling, and Spectroscopic Studies of D(Gaagcttc)2-Actinomycin D Complexes and its Host DNA; J.Am.Chem.Soc., 116:4154-, 1994; DOI: 10.1021/JA00089A002

実験手法

X-RAY DIFFRACTION (3 Å)