172D

MULTIPLE BINDING MODES OF ANTICANCER DRUG ACTINOMYCIN D: X-RAY, MOLECULAR MODELING, AND SPECTROSCOPIC STUDIES OF D(GAAGCTTC)2-ACTINOMYCIN D COMPLEXES AND ITS HOST DNA

Summary for 172D

Related173D
DescriptorDNA (5'-D(*GP*AP*AP*GP*CP*TP*TP*C)-3') (2 entities in total)
Functional Keywordsa-dna, double helix, dna
Total number of polymer chains4
Total molecular weight9706.47
Authors
Kamitori, S.,Takusagawa, F. (deposition date: 1994-04-18, release date: 1994-10-15, Last modification date: 2012-02-15)
Primary citation
Kamitori, S.,Takusagawa, F.
Multiple Binding Modes of Anticancer Drug Actinomycin D: X-Ray, Molecular Modeling, and Spectroscopic Studies of d(GAAGCTTC)2-Actinomycin D Complexes and Its Host DNA
J.Am.Chem.Soc., 116:4154-4165, 1994
Experimental method
X-RAY DIFFRACTION (3 Å)
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Structure validation

Clashscore35MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution