13FZ

Cryo-EM structure of human ZNFX1 dimer in complex with ssRNA and ATPgS

Summary for 13FZ

Entry DOI	10.2210/pdb13fz/pdb
EMDB information	77053
Descriptor	NFX1-type zinc finger-containing protein 1, RNA, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER (3 entities in total)
Functional Keywords	rna helicase, e3 ligase, rna
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	481112.87
Authors	Wang, F.,He, Q.,Li, H. (deposition date: 2026-05-05, release date: 2026-10-07)
Primary citation	He, Q.,Wang, F.,Rassool, F.V.,Baylin, S.B.,Li, H. Cryo-EM structures of autoinhibited and RNA-activated ZNFX1 helicase Nat Commun, 2026 Cited by DOI: 10.1038/s41467-026-78145-0 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.37 Å)

Structure validation