12VD

WT Human Aconitate Decarboxylase 1, citraconate-bound

Summary for 12VD

• Entry DOI: 10.2210/pdb12vd/pdb
• Descriptor: Cis-aconitate decarboxylase, SODIUM ION, DI(HYDROXYETHYL)ETHER, ... (6 entities in total)
• Functional Keywords: immune regulatory gene 1, oncoprotein, metabolism, immune system
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 101747.03

Authors

Runge, B.,Monteiro, D.C.F. (deposition date: 2026-04-20, release date: 2026-08-19)

• Primary citation: Runge, B.,Oktay, H.,Fucci, I.J.,Merten, E.M.,Tarasov, S.G.,Fan, L.,Monteiro, D.C.; Robust structural, kinetic and biophysical characterization of wild-type human ACOD1, selected mutants and their interaction with citraconate; J Struct Biol X, 14:100157-, 2026; DOI: 10.1016/j.yjsbx.2026.100157

Experimental method

X-RAY DIFFRACTION (1.22 Å)