12QJ

Pneumococcal choline binding CbpE surface protein bounds to 5992-2 Fab

Summary for 12QJ

• Entry DOI: 10.2210/pdb12qj/pdb
• EMDB information: 76684
• Descriptor: Choline binding protein E CbpE, 5992-2 Fab Heavy Chain, 5992-2 Fab Light Chain (3 entities in total)
• Functional Keywords: pneumococcal choline binding, cryoem, human monoclonal antibody, immune system
• Biological source: Streptococcus pneumoniae; More
• Total number of polymer chains: 3
• Total formula weight: 70576.07

Authors

McCormick, A.,Ghazi Esfahani, B.,Vidal, J.,Lee, F.E.,Tompkins, M.,McCaffrey, K.,Mousa, J. (deposition date: 2026-04-15, release date: 2026-06-03)

• Primary citation: McCormick, A.,Ghazi Esfahani, B.,Vida, J.,Lee, F.E.,Tompkins, M.,McCaffrey, K.,Mousa, J.; BROADLY REACTIVE HUMAN MONOCLONAL ANTIBODY TARGETING CONSERVED PNEUMOCOCCAL CHOLINE BINDING DOMAIN INCREASES PROTECTION AGAINST LETHAL PNEUMOCOCCAL INFECTION; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.35 Å)