12KE

Mycobacterial NDH-2 (type II NADH:quinone oxidoreductase) with tricyclic spirolactam inhibitor

This is a non-PDB format compatible entry.

Summary for 12KE

• Entry DOI: 10.2210/pdb12ke/pdb
• EMDB information: 76509
• Descriptor: NADH:ubiquinone reductase (non-electrogenic), FLAVIN-ADENINE DINUCLEOTIDE, (3S,4R,7aR,9S,11aR)-9-(bis{[4-(trifluoromethyl)phenyl]methyl}amino)-3-(propan-2-yl)octahydro[1,3]oxazolo[2,3-j]quinolin-5(6H)-one (3 entities in total)
• Functional Keywords: oxidoreductase, metabolism, flavoprotein, bioenergetics, membrane protein
• Biological source: Mycolicibacterium smegmatis MC2 155
• Total number of polymer chains: 2
• Total formula weight: 109353.73

Authors

Liang, Y.,Rubinstein, J.L. (deposition date: 2026-04-09, release date: 2026-09-30)

• Primary citation: Liang, Y.,Rubinstein, J.L.; Mycobacterial NDH-2 (type II NADH:quinone oxidoreductase) with tricyclic spirolactam inhibitor; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3 Å)