12CA

ALTERING THE MOUTH OF A HYDROPHOBIC POCKET. STRUCTURE AND KINETICS OF HUMAN CARBONIC ANHYDRASE II MUTANTS AT RESIDUE VAL-121

Summary for 12CA

• Entry DOI: 10.2210/pdb12ca/pdb
• Descriptor: CARBONIC ANHYDRASE II, ZINC ION, MERCURY (II) ION, ... (4 entities in total)
• Functional Keywords: lyase(oxo-acid)
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm : P00918
• Total number of polymer chains: 1
• Total formula weight: 29527.01

Authors

Nair, S.K.,Christianson, D.W. (deposition date: 1991-10-01, release date: 1992-10-15, Last modification date: 2024-02-07)

• Primary citation: Nair, S.K.,Calderone, T.L.,Christianson, D.W.,Fierke, C.A.; Altering the mouth of a hydrophobic pocket. Structure and kinetics of human carbonic anhydrase II mutants at residue Val-121.; J.Biol.Chem., 266:17320-17325, 1991; PubMed: 1910042

Experimental method

X-RAY DIFFRACTION (2.4 Å)