12BM

Human 19S proteasome bound to TXNL1 PITH domain state 2

Summary for 12BM

Entry DOI	10.2210/pdb12bm/pdb
EMDB information	76283
Descriptor	26S proteasome regulatory subunit 7, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 6, ... (23 entities in total)
Functional Keywords	proteasome, 19s, rp, txnl1, hydrolase
Biological source	Homo sapiens (human) More
Total number of polymer chains	19
Total formula weight	936283.94
Authors	Chen, X.,Negi, H.,Walters, K.J. (deposition date: 2026-03-25, release date: 2026-07-01)
Primary citation	Lee, K.,Negi, H.,Chen, X.,Atallah-Yunes, K.,Truslow, S.,Castelino, R.E.,Guest, M.,Ciancone, A.M.,Tarasov, S.G.,Chari, R.,Walters, K.J.,O'Reilly, F.J. Structures of dynamic interactors at native proteasomes by PhIX-MS and cryo-electron microscopy To Be Published,
Experimental method	ELECTRON MICROSCOPY (3.89 Å)

Structure validation