12BI

Moorella thermoacetica LarC (conformation 1)

Summary for 12BI

• Entry DOI: 10.2210/pdb12bi/pdb
• EMDB information: 76279
• Descriptor: Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein (1 entity in total)
• Functional Keywords: enzyme, nickel insertase, cyclometalliase, metal binding protein
• Biological source: Moorella thermoacetica (strain ATCC 39073 / JCM 9320)
• Total number of polymer chains: 6
• Total formula weight: 265534.19

Authors

Kim, K.H.,Wolfe, R. (deposition date: 2026-03-25, release date: 2026-07-29)

• Primary citation: Wolfe, R.,Turmo, A.,Velasquez-Rivertte, S.,Sui, D.,Granados-Villanueva, D.,Desguin, B.,Hu, J.,Hausinger, R.P.,Kim, K.H.; Structural and Functional Analysis of LarC, a CTP-Dependent Cyclometallase Required for Nickel-Pincer Nucleotide Cofactor Biosynthesis; Sci Adv, 2026

Experimental method

ELECTRON MICROSCOPY (3.97 Å)