12AK

Q108K:K40L:T51V:T53S:R58W:Y19W:L117E mutant of hCRBPII bound to fluorophore TD-1V-6

This is a non-PDB format compatible entry.

Replaces:  9PSZ

Summary for 12AK

• Entry DOI: 10.2210/pdb12ak/pdb
• Descriptor: Retinol-binding protein 2, (2Z)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}-4,4,4-trifluorobut-2-enal, ACETATE ION, ... (5 entities in total)
• Functional Keywords: human cellular retinol binding protein ii, hcrbpii, fluorescent protein, engineered protein, retinol binding protein, cytosolic protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 16205.09

Authors

Ghanbarpour, A.,Bingham, C.,Geiger, J.H. (deposition date: 2026-03-23, release date: 2026-04-01)

• Primary citation: Santos, E.,Ghanbarpour, A.,Chandra, I.,Bingham, C.,Vasileiou, C.,Geiger, J.H.,Borhan, C.; Exploring the Structure-Property Relationships of Protein/Fluorophore Complex; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.37 Å)