12AF

Crystal Structure of SARS-CoV-2 Mpro with UM-067

This is a non-PDB format compatible entry.

Summary for 12AF

• Entry DOI: 10.2210/pdb12af/pdb
• Descriptor: 3C-like proteinase nsp5, GLYCEROL, N-(trifluoroacetyl)-D-phenylalanyl-3-cyclopropyl-N-{(1Z,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-alaninamide, ... (5 entities in total)
• Functional Keywords: mpro, sars2, coronavirus, viral protease, main protease, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 1
• Total formula weight: 34450.15

Authors

Shaqra, A.M.,Adnan, S.F.Z.,Lee, L.T.,Iyer, V.,Jung, K.,Intravaia, L.E.,Kaur, J.,Schiffer, C.A. (deposition date: 2026-03-22, release date: 2026-04-22)

• Primary citation: Shaqra, A.M.,Adnan, S.F.Z.,Lee, L.T.,Iyer, V.,Jung, K.,Intravaia, L.E.,Kaur, J.,Schiffer, C.A.; Crystal Structure of SARS-CoV-2 Mpro with UM-067; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.87 Å)