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12AA

NMR structure and free-energy simulations for rational design of myotonic dystrophy RNA inhibitors

Summary for 12AA
Entry DOI10.2210/pdb12aa/pdb
DescriptorRNA (5'-R(*GP*AP*CP*AP*GP*CP*UP*GP*CP*UP*GP*UP*C)-3') (1 entity in total)
Functional Keywordsmyotonic dystrophy, rna complex, u-u internal loop, rna, rna duplex
Biological sourceHomo sapiens
Total number of polymer chains2
Total formula weight8267.00
Authors
Baisden, J.T.,Ainsley, J.,Ledeboer, M. (deposition date: 2026-03-21, release date: 2026-10-07)
Primary citationLedeboer, M.,Ainsley, J.,Baisden, J.T.,Ray, S.,Connolly, P.,Sinha, M.,Ha, V.,Sollomoni, I.,Angelbello, A.,Arsenault, M.,Bourque, E.,Skerlj, R.,Wang, Y.,Sun, Y.
NMR structure and free-energy simulations for rational design of myotonic dystrophy RNA inhibitors
To Be Published,
Experimental method
SOLUTION NMR
Structure validation

260626

PDB entries from 2026-10-07

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