12CA
ALTERING THE MOUTH OF A HYDROPHOBIC POCKET. STRUCTURE AND KINETICS OF HUMAN CARBONIC ANHYDRASE II MUTANTS AT RESIDUE VAL-121
Summary for 12CA
Entry DOI | 10.2210/pdb12ca/pdb |
Descriptor | CARBONIC ANHYDRASE II, ZINC ION, MERCURY (II) ION, ... (4 entities in total) |
Functional Keywords | lyase(oxo-acid) |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29527.01 |
Authors | Nair, S.K.,Christianson, D.W. (deposition date: 1991-10-01, release date: 1992-10-15, Last modification date: 2024-02-07) |
Primary citation | Nair, S.K.,Calderone, T.L.,Christianson, D.W.,Fierke, C.A. Altering the mouth of a hydrophobic pocket. Structure and kinetics of human carbonic anhydrase II mutants at residue Val-121. J.Biol.Chem., 266:17320-17325, 1991 Cited by PubMed: 1910042PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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