11WZ

MPXV polymerase-E5 primase core complex

Summary for 11WZ

• Entry DOI: 10.2210/pdb11wz/pdb
• EMDB information: 76148
• Descriptor: DNA polymerase, Uracil-DNA glycosylase, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*GP*CP*TP*C)-3'), ... (6 entities in total)
• Functional Keywords: mpxv, replisome, replication, viral protein, viral protein-dna complex, virus, viral protein-dna-rna complex, viral protein/dna
• Biological source: Monkeypox virus; More
• Total number of polymer chains: 7
• Total formula weight: 378535.40

Authors

Yu, Z.,Abarham, J. (deposition date: 2026-03-16, release date: 2026-09-02)

• Primary citation: Yu, Z.,Sathyanarayana, P.,Tan, J.M.J.T.,Hu, S.,Fan, X.,Gao, A.,Kranzusch, P.J.,Loparo, J.J.,Abraham, J.; Structure and operating principles of a monkeypox virus replisome; Nature, 2026; DOI: 10.1038/s41586-026-10937-2

Experimental method

ELECTRON MICROSCOPY (3.8 Å)