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11WR

Cryo-EM structure of Candida albicans fluoride channel FEX in complex with Fab fragment in LiCl

Summary for 11WR
Entry DOI10.2210/pdb11wr/pdb
Related9OP1
EMDB information76140
Descriptor10E8v4 Fab Heavy Chain, 10E8v4 Fab Light Chain, Transmembrane protein gp41,Fluoride export protein 1 (3 entities in total)
Functional Keywordsfluoride channel, fluoride exporter, fex, candida albicans, lithium, membrane protein
Biological sourceHomo sapiens
More
Total number of polymer chains3
Total formula weight86320.12
Authors
Kang, C.-Y.,Stockbridge, R.B. (deposition date: 2026-03-16, release date: 2026-08-19)
Primary citationKang, C.-Y.,Heidari, S.,Kolb, S.,An, M.,Ohi, M.D.,Torabifard, H.,Stockbridge, R.B.
The structural mechanism of fluoride channel inhibition by lithium in eukaryotes
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.56 Å)
Structure validation

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PDB entries from 2026-08-19

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