11TS

Crystal structure of apo alpha/beta-hydrolase macrolide esterase EstT from Sphingobacterium faecium (S126A mutant)

Summary for 11TS

Entry DOI	10.2210/pdb11ts/pdb
Descriptor	alpha/beta-hydrolase macrolide esterase EstT (2 entities in total)
Functional Keywords	alpha/beta-hydrolase, esterase, macrolide resistance, hydrolase
Biological source	Sphingobacterium faecium
Total number of polymer chains	5
Total formula weight	175394.28
Authors	Hemmings, M.Z.,Blanchet, J.,Kelly, E.T.R.,Berghuis, A.M. (deposition date: 2026-03-12, release date: 2026-04-08)
Primary citation	Kelly, E.T.R.,Myziuk, I.,Hemmings, M.Z.,Mulla, Z.,Blanchet, J.,Ruzzini, A.,Berghuis, A.M. Hydration and hydrolysis define antibiotic resistance conferred by macrolide esterases Biorxiv, 2026 Cited by DOI: 10.64898/2026.03.24.713787 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.19 Å)

Structure validation