11SE

Covalent stabilizer compound 8 for the interaction between 14-3-3 sigma and Estrogen receptor-alpha peptide

This is a non-PDB format compatible entry.

Summary for 11SE

• Entry DOI: 10.2210/pdb11se/pdb
• Descriptor: 14-3-3 protein sigma, Estrogen receptor, 3-chloro-5-{[(1S)-1-methoxy-1-methyl-3-oxo-1,3-dihydro-2-benzofuran-4-yl]oxy}-4H-1,2,6-thiadiazin-4-one, ... (6 entities in total)
• Functional Keywords: 14-3-3, adapter, phosphoserine, phosphothreonine, protein binding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 59773.50

Authors

Knapp, M.S.,Tang, J.Y. (deposition date: 2026-03-11, release date: 2026-08-26)

• Primary citation: Rama, J.,Skepper, C.K.; Covalent stabilizers of the interaction between 14-3-3 and Estrogen receptor-alpha; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.239 Å)