11SD

Covalent stabilizer compound 6 for the interaction between 14-3-3 sigma and Estrogen receptor-alpha peptide

This is a non-PDB format compatible entry.

Summary for 11SD

• Entry DOI: 10.2210/pdb11sd/pdb
• Descriptor: 14-3-3 protein sigma, Estrogen receptor, (2S)-2-(4-chlorophenyl)-2-cyclopentyl-N-{2-[(E)-iminomethyl]pyrimidin-5-yl}acetamide, ... (4 entities in total)
• Functional Keywords: 14-3-3, adapter, phosphoserine, phosphothreonine, protein binding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 60404.01

Authors

Knapp, M.S.,Tang, J.Y. (deposition date: 2026-03-11, release date: 2026-08-26, Last modification date: 2026-09-02)

• Primary citation: Rama, J.,Skepper, C.K.; Covalent stabilizers of the interaction between 14-3-3 and Estrogen receptor-alpha; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.816 Å)