11JC

RNA Vault Shoulder with ADPR bound, compact conformation, focused refinement (MVP/PARP4/TEP1 NADP sample)

Summary for 11JC

• Entry DOI: 10.2210/pdb11jc/pdb
• EMDB information: 75732
• Descriptor: Major vault protein, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL[HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE (3 entities in total)
• Functional Keywords: rna vault, complex, tep1, parp4, structural protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 3
• Total formula weight: 300036.25

Authors

Osinski, A.,Tagliabracci, V.S. (deposition date: 2026-02-26, release date: 2026-05-20)

• Primary citation: Osinski, A.,Mayro, B.,Lopez, V.A.,Schrad, J.,Choi, H.,Tomchick, D.R.,Pawlowski, K.,Forsberg, K.,Shahmoradian, S.H.,Tagliabracci, V.S.; TIR-like NADases act in bacterial immunity and the RNA vault; Biorxiv, 2026; DOI: 10.64898/2026.05.01.722283

Experimental method

ELECTRON MICROSCOPY (1.96 Å)