11HN

SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation bound to C77G12 (S2 local refinement)

Summary for 11HN

• Entry DOI: 10.2210/pdb11hn/pdb
• Related: 11HW
• EMDB information: 75697 75722
• Descriptor: Spike protein S2, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: s2prime, coronavirus, sars-cov-2, spike, fusion, entry, antiviral, structural genomics, seattle structural genomics center for infectious disease, ssgcid, viral protein-hydrolase complex, c77g12, viral protein
• Biological source: Saccharomyces cerevisiae S288C; More
• Total number of polymer chains: 3
• Total formula weight: 206016.04

Authors

McCallum, M.,Seattle Structural Genomics Center for Infectious Disease (SSGCID),Veesler, D. (deposition date: 2026-02-24, release date: 2026-03-18)

• Primary citation: McCallum, M.,Case, J.B.,Brown, J.,Diamond, M.,Veesler, D.; TMPRSS2-mediated coronavirus spike activation and inhibition; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.7 Å)