11HC

Effector complex from type IV-C CRISPR-Cas system

Summary for 11HC

• Entry DOI: 10.2210/pdb11hc/pdb
• EMDB information: 75685
• Descriptor: Cas10IVc, Cas5c, Cas7c, ... (8 entities in total)
• Functional Keywords: crispr-cas, nuclease, rna-guided, cas10, cas7, rna binding protein
• Biological source: Pyrococcus abyssi; More
• Total number of polymer chains: 17
• Total formula weight: 470270.77

Authors

Pittman, C.,Xu, C.,Catchpole, R.,Garrett, S.,Fuchs, R.,Makarova, K.,Koonin, E.,Zhao, P.,Wells, L.,Graveley, B.,Chu, X.,Ke, A.,Terns, M. (deposition date: 2026-02-23, release date: 2026-08-26)

• Primary citation: Pittman, C.,Xu, C.,Catchpole, R.,Garrett, S.,Fuchs, R.,Makarova, K.,Koonin, E.,Zhao, P.,Wells, L.,Graveley, B.,Chu, X.,Ke, A.,Terns, M.; Type IV-C CRISPR-Cas effector complex recognizes double-stranded DNA and switches on collateral cleavage of ssDNA and RNA; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.37 Å)