11SF

Covalent stabilizer compound 9 for the interaction between 14-3-3 sigma and Estrogen receptor-alpha peptide

This is a non-PDB format compatible entry.

Summary for 11SF

• Entry DOI: 10.2210/pdb11sf/pdb
• Descriptor: 14-3-3 protein sigma, Estrogen receptor, 2-chloro-1-{(2R,6S)-4-[2-(4-chlorophenyl)ethyl]-2,6-dimethylpiperazin-1-yl}ethan-1-one, ... (4 entities in total)
• Functional Keywords: 14-3-3, adapter, phosphoserine, phosphothreonine, protein binding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 59726.25

Authors

Knapp, M.S.,Tang, J.Y. (deposition date: 2026-03-11, release date: 2026-08-26, Last modification date: 2026-09-02)

• Primary citation: Rama, J.,Skepper, C.K.; Covalent stabilizers of the interaction between 14-3-3 and Estrogen receptor-alpha; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.24 Å)