11SF

Covalent stabilizer compound 9 for the interaction between 14-3-3 sigma and Estrogen receptor-alpha peptide

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	14-3-3 protein sigma	polymer	248	27807.1	2	UniProt (P31947)	Homo sapiens (human)	Epithelial cell marker protein 1,Stratifin
2	C, D (X, Y)	Estrogen receptor	polymer	15	1726.8	2	UniProt (P03372)	Homo sapiens	ER,ER-alpha,Estradiol receptor,Nuclear receptor subfamily 3 group A member 1
3	E, F (A, B)	2-chloro-1-{(2R,6S)-4-[2-(4-chlorophenyl)ethyl]-2,6-dimethylpiperazin-1-yl}ethan-1-one	non-polymer		329.3	2	Chemie (A1DAF)
4	G, H, I, J (A, B, X, Y)	water	water		18.0	104	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	59067.7
Non-Polymers*	Number of molecules	2
	Total formula weight	658.5
All*	Total formula weight	59726.2

*Water molecules are not included.