10WP

MPXV replisome bound to forked DNA

Summary for 10WP

• Entry DOI: 10.2210/pdb10wp/pdb
• EMDB information: 75504
• Descriptor: Uncoating factor OPG117, lagging strand, DNA polymerase, ... (7 entities in total)
• Functional Keywords: mpxv, replisome, replication, viral protein, virus
• Biological source: Monkeypox virus; More
• Total number of polymer chains: 11
• Total formula weight: 749392.93

Authors

Yu, Z.,Abraham, J. (deposition date: 2026-02-11, release date: 2026-09-02)

• Primary citation: Yu, Z.,Sathyanarayana, P.,Tan, J.M.J.T.,Hu, S.,Fan, X.,Gao, A.,Kranzusch, P.J.,Loparo, J.J.,Abraham, J.; Structure and operating principles of a monkeypox virus replisome; Nature, 2026; DOI: 10.1038/s41586-026-10937-2

Experimental method

ELECTRON MICROSCOPY (6.5 Å)