10LN

VT Ia tau filament from VT Case 1

Summary for 10LN

• Entry DOI: 10.2210/pdb10ln/pdb
• EMDB information: 75271
• Descriptor: Microtubule-associated protein tau (1 entity in total)
• Functional Keywords: microtubule-associated protein, structural protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 18
• Total formula weight: 147319.42

Authors

Watanabe, R.,Lee, E.B. (deposition date: 2026-01-27, release date: 2026-09-02)

• Primary citation: Watanabe, R.,Creekmore, B.C.,Darwich, N.F.,Smith, C.L.,Xu, H.,Baltazar, A.,Salphati, S.,Changolkar, L.,Hoxha, K.,Zhang, B.,O'Rourke, C.M.,Burslem, G.M.,Lee, V.M.-Y.,Chang, Y.-W.,Lee, E.B.; Repositioning of polyubiquitin alters the pathologic tau filament structure; Nat.Struct.Mol.Biol., 2026; DOI: 10.1038/s41594-026-01879-4

Experimental method

ELECTRON MICROSCOPY (2.92 Å)