10KA

Co-crystal Structure of CHI3L1 bound to DELC2 small molecule ligand

This is a non-PDB format compatible entry.

Summary for 10KA

• Entry DOI: 10.2210/pdb10ka/pdb
• Descriptor: Chitinase-3-like protein 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, (3aR,6aR)-2-(3-cyclopropyl-N-{[4-(pyridin-2-yl)phenyl]methyl}-D-alanyl)-N-[(2R)-1-(methylamino)-1-oxopentan-2-yl]hexahydrocyclopenta[c]pyrrole-3a(1H)-carboxamide, ... (4 entities in total)
• Functional Keywords: chi3l1, glycosyl hydrolase 18, glioblastoma, chi3l1-delc2 complex, del screening, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 91619.61

Authors

Upadhyay, S.,Zhang, L.,Teplova, M.,Gabr, M. (deposition date: 2026-01-22, release date: 2026-08-05)

• Primary citation: Upadhyay, S.,Zhang, L.,Teplova, M.,Gabr, M.; Co-crystal Structure of CHI3L1 bound to DELC2 small molecule ligand.; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.47 Å)