10GN

Nucleosome containing an 8oxoG at SHL+3

Summary for 10GN

• Entry DOI: 10.2210/pdb10gn/pdb
• EMDB information: 75156
• Descriptor: Histone H3.2, Histone H4, Histone H2A type 1, ... (6 entities in total)
• Functional Keywords: nucleosome, 8oxog, dna repair, dna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 10
• Total formula weight: 199399.67

Authors

Vito, A.F.,Ling, J.A.,Freudenthal, B.D. (deposition date: 2026-01-19, release date: 2026-07-22)

• Primary citation: Vito, A.F.,Ling, J.A.,Ferrara, J.C.,Jacques, C.S.,Gillet, N.,Gonzalez-Aleman, R.,Qiu, Y.,Hashemian, M.,Trasvina-Arenas, C.H.,David, S.S.,Delaney, S.,Bignon, E.,Freudenthal, B.D.; 8oxoG:A Is Structurally Accommodated in the Nucleosome Core Particle, Yet Inaccessible to MUTYH-Initiated DNA Repair; Biomolecules, 16:999-, 2026; DOI: 10.3390/biom16070999

Experimental method

ELECTRON MICROSCOPY (3 Å)