10GE
The eukaryotic translation initiation factor 2B from Homo sapiens with a L179V mutation in the delta subunit, A-state
Summary for 10GE
| Entry DOI | 10.2210/pdb10ge/pdb |
| EMDB information | 75148 |
| Descriptor | Translation initiation factor eIF2B subunit epsilon, Translation initiation factor eIF2B subunit delta, Translation initiation factor eIF2B subunit alpha, ... (7 entities in total) |
| Functional Keywords | complex, gef, translation, guanine nucleotide exchange factor |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 10 |
| Total formula weight | 424949.88 |
| Authors | Dalwadi, U.,Boone, M.,Croll, T.I.,Laughlin, T.G.,Frost, A.,Walter, P. (deposition date: 2026-01-19, release date: 2026-10-28) |
| Primary citation | Boone, M.,Dalwadi, U.,Deal, A.,Zhu, P.J.,Croll, T.I.,Yamazaki, M.,Prescott, K.,Minopoli, R.,Biscocho, I.,Wang, J.,Lee, D.J.,Arthur, C.P.,Laughlin, T.G.,Zhou, H.,Klope, M.T.,Egea, P.F.,Schoof, M.,Lawrence, R.,Renslo, A.R.,Costa-Mattioli, M.,Frost, A.,Walter, P. Stereoselective methyl-swapping demonstrates target specificity of cognitive enhancer Biorxiv, 2026 Cited by DOI: 10.64898/2026.02.04.700910PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.6 Å) |
Structure validation
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