9ZYT
Crystal Structure of BRD4 Bromodomain BD1 in Complex with Small Molecule PLX-3618
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (AAA, BBB) | Bromodomain-containing protein 4 | polymer | 124 | 14740.0 | 2 | UniProt (O60885) Pfam (PF00439) | Homo sapiens (human) | Protein HUNK1 |
| 2 | C, E (AAA, BBB) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 3 | D, F, G (AAA, BBB) | PLX-3618 | non-polymer | 601.7 | 3 | Chemie (A1C4W) PubChem (171904683) | |||
| 4 | H, I (AAA, BBB) | water | water | 18.0 | 292 | Chemie (HOH) |
Sequence modifications
AAA, BBB: 44 - 165 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Ser 42 | - | expression tag |
| Met 43 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29480.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1929.2 | |
| All* | Total formula weight | 31409.3 |
