9ZY1
Cryo-EM structure of the dimeric HIV-2 Vif-human APOBEC3H-CBFbeta complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (1, A) | Virion infectivity factor | polymer | 215 | 25044.9 | 2 | UniProt (Q9YTT9) | Human immunodeficiency virus 2 | |
| 2 | B, E (2, B) | Core-binding factor subunit beta | polymer | 182 | 21542.2 | 2 | UniProt (Q13951) | Homo sapiens (human) | CBF-beta,Polyomavirus enhancer-binding protein 2 beta subunit,PEA2-beta,PEBP2-beta,SL3-3 enhancer factor 1 subunit beta,SL3/AKV core-binding factor beta subunit |
| 3 | C, F (3, C) | Single-stranded DNA cytosine deaminase | polymer | 183 | 21763.1 | 2 | UniProt (B7TQM6) | Homo sapiens (human) | |
| 4 | G (D) | RNA (5'-R(P*UP*UP*UP*UP*UP*UP*UP*U)-3') | polymer | 8 | 2404.4 | 1 | synthetic construct | ||
| 5 | H (E) | RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*A)-3') | polymer | 8 | 2588.7 | 1 | synthetic construct | ||
| 6 | I, J (A, C) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) PubChem (32051) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 141693.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 141824.3 |
