9ZXD
Structure of AT118-R nanobody in complex with the angiotensin II type I receptor bound to L-162,313
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | AT118-R nanobody,Type-1 angiotensin II receptor with Soluble cytochrome b562 insertion | polymer | 582 | 65389.8 | 1 | UniProt (P30556) UniProt (P0ABE7) | synthetic construct | |
| 2 | B (C) | BAG2 Anti-BRIL Fab Heavy Chain | polymer | 231 | 24539.3 | 1 | synthetic construct | ||
| 3 | C (D) | BAG2 Anti-BRIL Fab Light Chain | polymer | 215 | 23541.2 | 1 | synthetic construct | ||
| 4 | D (A) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 1 | Chemie (Y01) | |||
| 5 | E (A) | butyl [3-{4-[(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl]phenyl}-5-(2-methylpropyl)thiophene-2-sulfonyl]carbamate | non-polymer | 582.8 | 1 | Chemie (A1C42) |
Sequence modifications
A: -134 - 1 (PDB: 9ZXD)
A: 2 - 226 (UniProt: P30556)
A: 227 - 330 (UniProt: P0ABE7)
A: 1235 - 1319 (UniProt: P30556)
A: 2 - 226 (UniProt: P30556)
A: 227 - 330 (UniProt: P0ABE7)
| PDB | External Database | Details |
|---|---|---|
| Trp 232 | Met 29 | engineered mutation |
| Ile 327 | His 124 | engineered mutation |
| Leu 331 | - | linker |
| Glu 332 | - | linker |
| Arg 333 | - | linker |
| Ala 334 | - | linker |
| Arg 335 | - | linker |
| Ser 336 | - | linker |
| Thr 337 | - | linker |
| Leu 338 | - | linker |
| Asp 339 | - | linker |
| Lys 340 | - | linker |
| Leu 341 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Gly 1320 | - | expression tag |
| Gly 1321 | - | expression tag |
| Ser 1322 | - | expression tag |
| Ser 1323 | - | expression tag |
| Leu 1324 | - | expression tag |
| Glu 1325 | - | expression tag |
| Val 1326 | - | expression tag |
| Leu 1327 | - | expression tag |
| Phe 1328 | - | expression tag |
| Gln 1329 | - | expression tag |
| Gly 1330 | - | expression tag |
| Pro 1331 | - | expression tag |
| Thr 1332 | - | expression tag |
| Glu 1333 | - | expression tag |
| Thr 1334 | - | expression tag |
| Ser 1335 | - | expression tag |
| Gln 1336 | - | expression tag |
| Val 1337 | - | expression tag |
| Ala 1338 | - | expression tag |
| Pro 1339 | - | expression tag |
| Ala 1340 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 113470.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1069.5 | |
| All* | Total formula weight | 114539.8 |
