9ZVL

CryoEM structure of H5N1 A/Texas/37/2024 HA bound to Fab H83

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Hemagglutinin	polymer	576	65585.8	3	UniProt (A0AAX6NNG0)	Influenza A virus
2	D, F, H (H, D, E)	Fab H83 Heavy Chain	polymer	258	28085.6	3		Homo sapiens
3	E, G, I (L, F, G)	Fab H83 Light Chain	polymer	234	25432.4	3		Homo sapiens
4	J, K, L, M, N... (A, B, C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	12	Chemie (NAG) PubChem (24139)

Sequence modifications

A, B, C: -11 - 505 (UniProt: A0AAX6NNG0)

PDB	External Database	Details
Ile 199	Thr 211	conflict
-	Glu 340	deletion
Arg 330	Lys 341	conflict
Arg 333	Lys 344	conflict
Gly 506	-	expression tag
Ser 507	-	expression tag
Ser 508	-	expression tag
Gly 509	-	expression tag
Ser 510	-	expression tag
Ser 511	-	expression tag
Gly 512	-	expression tag
Tyr 513	-	expression tag
Ile 514	-	expression tag
Pro 515	-	expression tag
Glu 516	-	expression tag
Ala 517	-	expression tag
Pro 518	-	expression tag
Arg 519	-	expression tag
Asp 520	-	expression tag
Gly 521	-	expression tag
Gln 522	-	expression tag
Ala 523	-	expression tag
Tyr 524	-	expression tag
Val 525	-	expression tag
Arg 526	-	expression tag
Lys 527	-	expression tag
Asp 528	-	expression tag
Gly 529	-	expression tag
Glu 530	-	expression tag
Trp 531	-	expression tag
Val 532	-	expression tag
Leu 533	-	expression tag
Leu 534	-	expression tag
Ser 535	-	expression tag
Thr 536	-	expression tag
Phe 537	-	expression tag
Leu 538	-	expression tag
Gly 539	-	expression tag
His 540	-	expression tag
His 541	-	expression tag
His 542	-	expression tag
His 543	-	expression tag
His 544	-	expression tag
His 545	-	expression tag
His 546	-	expression tag
His 547	-	expression tag
His 548	-	expression tag
Gly 549	-	expression tag
Gly 550	-	expression tag
Ser 551	-	expression tag
Gly 552	-	expression tag
Leu 553	-	expression tag
Asn 554	-	expression tag
Asp 555	-	expression tag
Ile 556	-	expression tag
Phe 557	-	expression tag
Glu 558	-	expression tag
Ala 559	-	expression tag
Gln 560	-	expression tag
Lys 561	-	expression tag
Ile 562	-	expression tag
Glu 563	-	expression tag
Trp 564	-	expression tag
His 565	-	expression tag
Glu 566	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	9
	Total formula weight	357311.2
Non-Polymers*	Number of molecules	12
	Total formula weight	2654.5
All*	Total formula weight	359965.7

*Water molecules are not included.