9ZUK

Crystal structure of BPTF bromodomain bound to BZ1

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Nucleosome-remodeling factor subunit BPTF	polymer	123	14455.4	2	UniProt (Q12830) Pfam (PF00439)	Homo sapiens (human)	Bromodomain and PHD finger-containing transcription factor,Fetal Alz-50 clone 1 protein,Fetal Alzheimer antigen
2	C, D (A, B)	5-[4-(2-aminoethyl)anilino]-4-chloro-2-methylpyridazin-3(2H)-one	non-polymer		278.7	2	Chemie (A1C4C)
3	E, F (A, B)	water	water		18.0	292	Chemie (HOH)

Sequence modifications

A, B: 2917 - 3037 (UniProt: Q12830)

PDB	External Database	Details
Ser 2915	-	expression tag
Met 2916	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	28910.8
Non-Polymers*	Number of molecules	2
	Total formula weight	557.5
All*	Total formula weight	29468.3

*Water molecules are not included.