9ZU3

Crystal structure of BRD9 bromodomain bound to BZ1

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Bromodomain-containing protein 9	polymer	129	14989.2	2	UniProt (Q9H8M2) Pfam (PF00439)	Homo sapiens (human)	Rhabdomyosarcoma antigen MU-RMS-40.8
2	C, G (A, B)	5-[4-(2-aminoethyl)anilino]-4-chloro-2-methylpyridazin-3(2H)-one	non-polymer		278.7	2	Chemie (A1C4C)
3	D, E, F (A)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
4	H, I (A, B)	water	water		18.0	390	Chemie (HOH)

Sequence modifications

A, B: 134 - 239 (UniProt: Q9H8M2)

PDB	External Database	Details
Met 111	-	initiating methionine
Gly 112	-	expression tag
Ser 113	-	expression tag
Ser 114	-	expression tag
His 115	-	expression tag
His 116	-	expression tag
His 117	-	expression tag
His 118	-	expression tag
His 119	-	expression tag
His 120	-	expression tag
His 121	-	expression tag
His 122	-	expression tag
His 123	-	expression tag
Ser 124	-	expression tag
Ser 125	-	expression tag
Gly 126	-	expression tag
Glu 127	-	expression tag
Asn 128	-	expression tag
Leu 129	-	expression tag
Tyr 130	-	expression tag
Phe 131	-	expression tag
Gln 132	-	expression tag
Gly 133	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	29978.3
Non-Polymers*	Number of molecules	5
	Total formula weight	845.7
All*	Total formula weight	30824.0

*Water molecules are not included.