9ZT7

SARS-CoV-2 S2 in complex with COV2-2509

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	COV2-2509 Fab-Heavy chain	polymer	224	23965.9	1		Homo sapiens
2	B (B)	COV2-2509 Fab-Light chain	polymer	214	23285.8	1		Homo sapiens
3	C, D, E (C, D, E)	Spike protein S2	polymer	474	52342.1	3	UniProt (P0DTC2)	Homo sapiens (human)
4	F, G, H, I, J... (F, G, H, I, J...)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	10	In PDB GlyTouCan (G42666HT)
5	P, Q, R, S (C, D, E)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)

Sequence modifications

C, D, E: 698 - 1161 (UniProt: P0DTC2)

PDB	External Database	Details
Cys 704	Ser 704	engineered mutation
Cys 790	Lys 790	engineered mutation
Cys 880	Gly 880	engineered mutation
Cys 888	Phe 888	engineered mutation
Pro 892	Ala 892	engineered mutation
Pro 899	Ala 899	engineered mutation
Pro 942	Ala 942	engineered mutation
Phe 961	Thr 961	engineered mutation
Pro 986	Lys 986	engineered mutation
Pro 987	Val 987	engineered mutation
Trp 991	Val 991	engineered mutation
Trp 998	Thr 998	engineered mutation
Gly 1162	-	expression tag
Ser 1163	-	expression tag
His 1164	-	expression tag
His 1165	-	expression tag
His 1166	-	expression tag
His 1167	-	expression tag
His 1168	-	expression tag
His 1169	-	expression tag
His 1170	-	expression tag
His 1171	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	204277.9
Branched	Number of molecules	10
	Total formula weight	4244.0
Non-Polymers*	Number of molecules	4
	Total formula weight	884.8
All*	Total formula weight	209406.7

*Water molecules are not included.