9ZRK
Cryo-EM structure of KCa3.1_I/calmodulin channel in complex with SKA111.
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Intermediate conductance calcium-activated potassium channel protein 4 | polymer | 360 | 40753.6 | 4 | UniProt (O15554) Pfam (PF03530) Pfam (PF07885) Pfam (PF02888) | Homo sapiens (human) | SKCa 4,SKCa4,hSK4,Gardos channel,IKCa1,hIK1,KCa3.1,Putative Gardos channel,hKCa4 |
| 2 | E, F, G, H (E, F, G, H) | Calmodulin-1 | polymer | 146 | 16521.1 | 4 | UniProt (P0DP23) Pfam (PF13499) | Homo sapiens (human) | |
| 3 | I, N, O, P (A, B, C, D) | 5-methylnaphtho[1,2-d][1,3]thiazol-2-amine | non-polymer | 214.3 | 4 | Chemie (A1C3U) | |||
| 4 | J, K, L, M (A) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 5 | AA, BA, CA, DA, EA... (G, H, E, F) | CALCIUM ION | non-polymer | 40.1 | 16 | Chemie (CA) |
Sequence modifications
A, B, C, D: 9 - 386 (UniProt: O15554)
| PDB | External Database | Details |
|---|---|---|
| - | Gly 124 | deletion |
| - | Pro 125 | deletion |
| - | Pro 126 | deletion |
| - | Cys 127 | deletion |
| - | Val 128 | deletion |
| - | Gln 129 | deletion |
| - | Asp 130 | deletion |
| - | Leu 131 | deletion |
| - | Gly 132 | deletion |
| - | Ala 133 | deletion |
| - | Pro 134 | deletion |
| - | Leu 135 | deletion |
| - | Thr 136 | deletion |
| - | Ser 137 | deletion |
| - | Pro 138 | deletion |
| - | Gln 139 | deletion |
| - | Pro 140 | deletion |
| - | Trp 141 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 229098.7 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 1654.8 | |
| All* | Total formula weight | 230753.4 |
