9ZPZ
CNGA1 channel intermediate state in nanodisc with brain PIP2 cGMP-bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Cyclic nucleotide-gated channel alpha-1 | polymer | 559 | 64519.2 | 4 | UniProt (P29973) Pfam (PF00520) Pfam (PF00027) Pfam (PF16526) | Homo sapiens (human) | CNG channel alpha-1,CNG-1,CNG1,Cyclic nucleotide-gated channel,photoreceptor,Rod photoreceptor cGMP-gated cation channel subunit alpha,cGMP-gated cation channel alpha-1 |
| 2 | BA, E, OA, S (C, A, D, B) | CYCLIC GUANOSINE MONOPHOSPHATE | non-polymer | 345.2 | 4 | Chemie (PCG) | |||
| 3 | CA, F, PA, T (C, A, D, B) | CHOLESTEROL | non-polymer | 386.7 | 4 | Chemie (CLR) | |||
| 4 | AA, DA, EA, FA, G... (C, A, D, B) | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 787.1 | 28 | Chemie (PCW) | |||
| 5 | IA, L (C, A) | [(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8Z)-icosa-5,8,11,14-tetraenoate | non-polymer | 1047.1 | 2 | Chemie (PT5) | |||
| 6 | KA, LA, P, Q, Z (C, A, B) | POTASSIUM ION | non-polymer | 39.1 | 5 | Chemie (K) |
Sequence modifications
A, B, C, D: 144 - 690 (UniProt: P29973)
| PDB | External Database | Details |
|---|---|---|
| Asp 132 | - | expression tag |
| Tyr 133 | - | expression tag |
| Lys 134 | - | expression tag |
| Asp 135 | - | expression tag |
| Asp 136 | - | expression tag |
| Asp 137 | - | expression tag |
| Asp 138 | - | expression tag |
| Lys 139 | - | expression tag |
| Gly 140 | - | expression tag |
| Gly 141 | - | expression tag |
| Ser 142 | - | expression tag |
| Ala 143 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 258077.0 | |
| Non-Polymers* | Number of molecules | 43 |
| Total formula weight | 27256.5 | |
| All* | Total formula weight | 285333.4 |
