9ZPW
CNGA1 channel intermediate state in nanodisc cGMP-bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Cyclic nucleotide-gated channel alpha-1 | polymer | 559 | 64519.2 | 4 | UniProt (P29973) Pfam (PF00520) Pfam (PF00027) Pfam (PF16526) | Homo sapiens (human) | CNG channel alpha-1,CNG-1,CNG1,Cyclic nucleotide-gated channel,photoreceptor,Rod photoreceptor cGMP-gated cation channel subunit alpha,cGMP-gated cation channel alpha-1 |
| 2 | DA, E, MA, T (C, A, D, B) | CYCLIC GUANOSINE MONOPHOSPHATE | non-polymer | 345.2 | 4 | Chemie (PCG) | |||
| 3 | EA, F, NA, U (C, A, D, B) | CHOLESTEROL | non-polymer | 386.7 | 4 | Chemie (CLR) | |||
| 4 | AA, BA, CA, FA, G... (B, C, A, D) | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 787.1 | 28 | Chemie (PCW) | |||
| 5 | N, O, P, Q, R... (A, D) | POTASSIUM ION | non-polymer | 39.1 | 6 | Chemie (K) |
Sequence modifications
A, B, C, D: 144 - 690 (UniProt: P29973)
| PDB | External Database | Details |
|---|---|---|
| Asp 132 | - | expression tag |
| Tyr 133 | - | expression tag |
| Lys 134 | - | expression tag |
| Asp 135 | - | expression tag |
| Asp 136 | - | expression tag |
| Asp 137 | - | expression tag |
| Asp 138 | - | expression tag |
| Lys 139 | - | expression tag |
| Gly 140 | - | expression tag |
| Gly 141 | - | expression tag |
| Ser 142 | - | expression tag |
| Ala 143 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 258077.0 | |
| Non-Polymers* | Number of molecules | 42 |
| Total formula weight | 25201.4 | |
| All* | Total formula weight | 283278.4 |
