9ZP9

CryoEM structure of DNA-PK bound to N7 nucleosome, state 1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E (A, E)	Histone H3	polymer	112	12830.0	2	UniProt (A0A310TTQ1) Pfam (PF00125)	Xenopus laevis (African clawed frog)
2	B, F (B, F)	Histone H4	polymer	87	9990.8	2	UniProt (P84048)	Xenopus laevis (African clawed frog)
3	C, G (C, G)	Histone H2A	polymer	111	12183.2	2	UniProt (A0A974HJ06)	Xenopus laevis (African clawed frog)
4	D, H (D, H)	Histone H2B	polymer	96	10792.4	2	UniProt (A0A8J1LZU9) Pfam (PF00125)	Xenopus laevis (African clawed frog)
5	I (I)	DNA (154-MER)	polymer	154	47768.4	1		Homo sapiens
6	J (J)	DNA (154-MER)	polymer	154	47306.2	1		Homo sapiens
7	K (K)	X-ray repair cross-complementing protein 6	polymer	609	69945.0	1	UniProt (P12956) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730) Pfam (PF02037)	Homo sapiens (human)
8	L (L)	X-ray repair cross-complementing protein 5	polymer	732	82812.4	1	UniProt (G3R763) Pfam (PF08785) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730)	Homo sapiens (human)
9	M (M)	DNA-dependent protein kinase catalytic subunit	polymer	4128	469673.2	1	UniProt (P78527) Pfam (PF20502) Pfam (PF08163) Pfam (PF19704) Pfam (PF02259) Pfam (PF00454) Pfam (PF02260)	Homo sapiens (human)
10	N (N)	Unknown peptide	polymer	20	1720.1	1		Homo sapiens

Sequence modifications

C, G: 10 - 120 (UniProt: A0A974HJ06)

PDB	External Database	Details
Ser 19	Thr 20	conflict
Arg 99	Gly 100	conflict

L: 1 - 732 (UniProt: G3R763)

PDB	External Database	Details
Gln 663	Arg 663	conflict

Contents of the asymmetric unit

Polymers	Number of chains	14
	Total formula weight	810818.2
All*	Total formula weight	810818.2

*Water molecules are not included.