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9ZO9

KRAS G13D Mutant in Complex with GDP and Compound 6.

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Isoform 2B of GTPase KRaspolymer17119461.81UniProt (P01116)
Pfam (PF00071)
Homo sapiens (human)K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras
2B
(A)
(3R)-1-[(7P)-8-fluoro-2-{[(2R,4R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}-7-(3-hydroxynaphthalen-1-yl)pyrido[4,3-d]pyrimidin-4-yl]piperidin-3-olnon-polymer547.61Chemie (A1C3J)
3C
(A)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
4D
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
PubChem (888)
5E, F
(A)
PHOSPHATE IONnon-polymer95.02Chemie (PO4)
PubChem (1061)
6G
(A)
waterwater18.0160Chemie (HOH)
Sequence modifications
A: 1 - 169 (UniProt: P01116)
PDBExternal DatabaseDetails
Gly -1-expression tag
Pro 0-expression tag
Asp 13Gly 13engineered mutation
Ser 51Cys 51engineered mutation
Leu 80Cys 80engineered mutation
Ser 118Cys 118engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight19461.8
Non-Polymers*Number of molecules5
Total formula weight1205.0
All*Total formula weight20666.9
*Water molecules are not included.

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PDB entries from 2026-08-05

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