9ZNX

Dimer of tubulin folding cofactors D and E bound to beta tubulin in the back to back orientation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (E, Y)	Tubulin-specific chaperone E	polymer	527	59422.0	2	UniProt (Q15813)	Homo sapiens (human)	Tubulin-folding cofactor E
2	C, E (D, N)	Tubulin-specific chaperone D	polymer	1205	134214.1	2	UniProt (Q9BTW9)	Homo sapiens (human)	Beta-tubulin cofactor D,tfcD,SSD-1,Tubulin-folding cofactor D
3	D, F (B, G)	Tubulin beta chain	polymer	447	49973.8	2	UniProt (A0A7E5X115)	Trichoplusia ni (cabbage looper)
4	G, H (B, G)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	2	Chemie (GDP)

Sequence modifications

D, N: 0 - 1192 (UniProt: Q9BTW9)

PDB	External Database	Details
Met -13	-	initiating methionine
Trp -12	-	expression tag
Ser -11	-	expression tag
His -10	-	expression tag
Pro -9	-	expression tag
Gln -8	-	expression tag
Phe -7	-	expression tag
Glu -6	-	expression tag
Lys -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	487219.9
Non-Polymers*	Number of molecules	2
	Total formula weight	886.4
All*	Total formula weight	488106.3

*Water molecules are not included.