9ZNU
Cryo-EM structure of L9-yd19 in complex with Plasmodium falciparum circumsporozoite protein (PfCSP) Kenya2-3 strain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G, I (H, I, J, K, P) | L9-yd19 heavy chain | polymer | 220 | 23632.4 | 5 | synthetic construct | ||
| 2 | B, D, F, H, J (L, M, N, O, Q) | L9-yd19 light chain | polymer | 214 | 23541.2 | 5 | synthetic construct | ||
| 3 | K (G) | Circumsporozoite protein | polymer | 335 | 36216.0 | 1 | UniProt (Q8I9H7) | Plasmodium falciparum (malaria parasite P. falciparum) | CS |
| 4 | L (R) | L9-yd19 heavy chain | polymer | 120 | 13383.9 | 1 | synthetic construct | ||
| 5 | M (S) | L9-yd19 light chain | polymer | 107 | 11781.2 | 1 | synthetic construct |
Sequence modifications
G: 2 - 319 (UniProt: Q8I9H7)
| PDB | External Database | Details |
|---|---|---|
| Ser 6 | Cys 25 | conflict |
| Ser 47 | Lys 66 | conflict |
| Ser 48 | Lys 67 | conflict |
| Ala 51 | Arg 70 | conflict |
| Gly 320 | - | expression tag |
| Ser 321 | - | expression tag |
| Gly 322 | - | expression tag |
| Leu 323 | - | expression tag |
| Asn 324 | - | expression tag |
| Asp 325 | - | expression tag |
| Ile 326 | - | expression tag |
| Phe 327 | - | expression tag |
| Glu 328 | - | expression tag |
| Ala 329 | - | expression tag |
| Gln 330 | - | expression tag |
| Lys 331 | - | expression tag |
| Ile 332 | - | expression tag |
| Glu 333 | - | expression tag |
| Trp 334 | - | expression tag |
| His 335 | - | expression tag |
| Glu 336 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 13 |
| Total formula weight | 297249.1 | |
| All* | Total formula weight | 297249.1 |
