9ZNN
Cryo-EM structure of human UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) in complex with APPB
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase | polymer | 419 | 47312.9 | 2 | UniProt (Q9H3H5) | Homo sapiens (human) | GlcNAc-1-P transferase,G1PT,GPT,N-acetylglucosamine-1-phosphate transferase |
| 2 | C, F (A, B) | 4-({(2S,3S)-1-amino-3-{[(2S,3R,4S,5R)-5-(aminomethyl)-3,4-dihydroxyoxolan-2-yl]oxy}-3-[(2S,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]-1-oxopropan-2-yl}amino)-N-[(4-{4-[4-(trifluoromethoxy)phenoxy]piperidin-1-yl}phenyl)methyl]butanamide (non-preferred name) | non-polymer | 881.8 | 2 | Chemie (A1C3G) | |||
| 3 | D, E (A, B) | (2R)-3-{[(S)-[(2R)-2,3-dihydroxypropoxy](hydroxy)phosphoryl]oxy}-2-{[(9Z)-octadec-9-enoyl]oxy}propyl (9Z)-octadec-9-enoate | non-polymer | 775.0 | 2 | Chemie (A1C3H) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 80 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 408 (UniProt: Q9H3H5)
| PDB | External Database | Details |
|---|---|---|
| Gly 409 | - | expression tag |
| Ser 410 | - | expression tag |
| Ser 411 | - | expression tag |
| Ala 412 | - | expression tag |
| Ser 413 | - | expression tag |
| Glu 414 | - | expression tag |
| Asn 415 | - | expression tag |
| Leu 416 | - | expression tag |
| Tyr 417 | - | expression tag |
| Phe 418 | - | expression tag |
| Gln 419 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 94625.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 3313.8 | |
| All* | Total formula weight | 97939.7 |
