9ZN6
Structure of rabbit RyR1 complexed with FKBP12.6 and calmodulin in the presence of dantrolene, ADP, 4-chloro-m-cresol, caffeine, and Mg2+
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (E, F, G, H) | Peptidyl-prolyl cis-trans isomerase FKBP1B | polymer | 107 | 11667.3 | 4 | UniProt (P68106) Pfam (PF00254) | Homo sapiens (human) | PPIase FKBP1B,12.6 kDa FK506-binding protein,FKBP-12.6,FK506-binding protein 1B,FKBP-1B,Immunophilin FKBP12.6,Rotamase,h-FKBP-12 |
| 2 | E, F, G, H (I, J, K, L) | Calmodulin-1 | polymer | 148 | 16790.4 | 4 | UniProt (P0DP23) Pfam (PF13499) | Homo sapiens (human) | |
| 3 | I, J, K, L (A, D, B, C) | Ryanodine receptor 1 | polymer | 5037 | 565908.6 | 4 | UniProt (P11716) Pfam (PF08709) Pfam (PF01365) Pfam (PF02026) Pfam (PF08454) Pfam (PF06459) Pfam (PF00520) Pfam (PF02815) Pfam (PF00622) Pfam (PF21119) | Oryctolagus cuniculus (rabbit) | RYR-1,RyR1,Skeletal muscle calcium release channel,Skeletal muscle ryanodine receptor,Skeletal muscle-type ryanodine receptor,Type 1 ryanodine receptor |
| 4 | EA, M, NA, V (B, A, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) PubChem (32051) | |||
| 5 | BA, FA, KA, N, OA... (D, B, A, C) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 8 | Chemie (ADP) | |||
| 6 | GA, O, PA, X (B, A, C, D) | Dantrolene | non-polymer | 314.3 | 4 | Chemie (U1C) PubChem (5378825) | |||
| 7 | AA, HA, IA, JA, P... (D, B, A, C) | 4-CHLORO-3-METHYLPHENOL | non-polymer | 142.6 | 12 | Chemie (43M) PubChem (1732) | |||
| 8 | CA, LA, T, UA (D, B, A, C) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) PubChem (271) | |||
| 9 | DA, MA, U, VA (D, B, A, C) | CAFFEINE | non-polymer | 194.2 | 4 | Chemie (CFF) PubChem (2519) | |||
| 10 | AB, BB, CB, DB, EB... (I, J, K, L, A...) | water | water | 18.0 | 3740 | Chemie (HOH) |
Sequence modifications
I, J, K, L: 0 - 146 (UniProt: P0DP23)
| PDB | External Database | Details |
|---|---|---|
| His -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 2377465.5 | |
| Non-Polymers* | Number of molecules | 36 |
| Total formula weight | 7584.3 | |
| All* | Total formula weight | 2385049.8 |
